Friday, November 25, 2011
Can Horses 'Watch and Learn'?
Horse Health Lecture Series Schedule Announced
...
Thursday, November 24, 2011
An inconvenient truth: global worming and anthelmintic resistance
Source: Veterinary Parasitology, Available online 19 November 2011
R.M. Kaplan, A.N. Vidyashankar
Over the past 10-15 years, we have witnessed a rapid increase in both the prevalence and magnitude of anthelmintic resistance, and this increase appears to be a worldwide phenomenon. Reports of anthelmintic resistance to multiple drugs in individual parasite species, and in multiple parasite species across virtually all livestock hosts, are increasingly common. In addition, since the introduction of ivermectin in 1981, no novel anthelmintic classes were developed and introduced for use in livestock until recently with the launch of monepantel in New Zealand. Thus, livestock producers are often left with few options for effective treatment against many important parasite species. While new anthelmintic classes with novel mechanisms of action could potentially solve this problem, new drugs are extremely expensive to develop, and can be expected to be more expensive than older drugs. Thus, it seems clear that the “Global Worming” approach that has taken hold over the past 40-50 years must change, and livestock producers must develop a new vision for parasite control and sustainability of production. Furthermore, parasitologists must improve methods for study design and data analysis that are used for diagnosing anthelmintic resistance, especially for the fecal egg count reduction test (FECRT). Currently, standards for diagnosis of anthelmintic resistance using FECRT exist only for sheep. Lack of standards in horses and cattle and arbitrarily defined cutoffs for defining resistance, combined with inadequate analysis of the data, mean that errors in assigning resistance status are common. Similarly, the lack of standards makes it difficult to compare data among different studies. This problem needs to be addressed, because as new drugs are introduced now and in the future, the lack of alternative treatments will make early and accurate diagnosis of anthelmintic resistance increasingly important.
Assessing Lameness Severity in Horses with Chronic Laminitis
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Purdue: Indiana's horse industry generates $2B a year from variety of horse ...
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UK-Led Kentucky Equine Survey launches
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New dressage app to help event riders remember their test
Animal success stories pave the way for human stem-cell therapy trials
Standing Laparoscopic Peritoneal Flap Hernioplasty Technique for Preventing Recurrence of Acquired Strangulating Inguinal Herniation in Stallions
Objective
To describe a standing laparoscopic peritoneal flap hernioplasty (PFH) technique for closure of the vaginal ring, and to evaluate its effect on prevention of recurrent herniation in stallions, previously treated for acquired strangulating inguinal hernia (SIH).
Study Design
Case series.
Animals
Stallions (n = 30) aged 3–15 that had previous acquired SIH.
Methods
Bilateral standing laparoscopic PFH was performed on 30 stallions that had previous acquired SIH treated without castration. The vaginal rings were approached from 3 portals, 2 in the paralumbar fossa and a 3rd between the 17th and 18th ribs on the ipsilateral side. A large inverted U-shaped peritoneal flap was dissected from the abdominal wall proximal and cranial to the vaginal ring, reflected caudally over the vaginal ring, and secured to the abdominal wall with laparoscopic staples. In the first 11 stallions, only the cranial and mid third of the vaginal ring was covered. For the next 19 stallions, complete closure of the vaginal ring including the entire caudal aspect of the vaginal ring was achieved.
Results
SIH recurrence occurred in 4 of 11 stallions with incomplete ring closure whereas no SIH recurrence occurred when the entire vaginal ring was closed. No major complications occurred and cosmetic outcome was excellent. All breeding stallions were successfully used for breeding.
Conclusion
Standing laparoscopic closure of the vaginal ring using a PFH is an effective way to prevent recurrence of SIH provided the entire vaginal ring, including the caudal aspect is covered by the flap. There seems to be no effect on subsequent fertility.
Attempted Medical Management of Suspected Ascending Colon Displacement in Horses
Objective
To determine the success of medical management of suspected displacement of the ascending (large) colon in horses.
Study Design
Retrospective case series.
Animals
Horses (n = 127) with suspected large colon displacement.
Methods
Medical records (January 1998–September 2008) of horses admitted for colic were reviewed. Suspected large colon displacement was diagnosed from clinical examination and in some cases, subsequent surgical examination. Medically managed horses were exercised and administered intravenous fluids and analgesia. Horses with suspected left dorsal displacement (LDD) of the large colon were also administered phenylephrine.
Results
Medical management had a high success rate for treatment of suspected right dorsal displacement (RDD) (64%) and LDD (76%) of the large colon; 4 horses died (1) or were euthanatized (3) and 36 horses had surgery. Of 127 horses treated medically or surgically for a colon displacement, 94% survived to hospital discharge.
Conclusions
Horses with suspected RDD or LDD of the large colon may respond to medical management including exercise.
Saddle Up Safely Wins Safety Award
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Laminitis Treatment with Stem Cells
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Wednesday, November 23, 2011
Vertical head and trunk movement adaptations of sound horses trotting in a circle on a hard surface
Source: The Veterinary Journal, Available online 20 November 2011
Sandra D. Starke, Egbert Willems, Stephen A. May, Thilo Pfau
Trotting a horse in circles is a standard and important part of the subjective equine lameness examination, yet objective data on this form of locomotion are sparse. The aim of this study was to investigate the effect of trotting in a circle on head and trunk movement symmetry. Vertical movements of the head, withers, os sacrum and left and right tuber coxae were measured using inertial sensors as 12 sound horses were trotted on a hard surface in a straight line and in a circle on both reins. Seven asymmetry measures and hip hike were calculated for each horse for at least nine strides of comparable stride duration across the three conditions (deviation on horse level ⩽3.7% stride duration).Trotting in a circle introduced systematic changes to the movement pattern of all five body landmarks, affecting most asymmetry measures. On average the asymmetry magnitude was comparable for midline locations between reins and for the tuber coxae on opposite reins with few exceptions, although individual horses showed unsystematic differences between the two reins. The results from this study showed that the thresholds for objective discrimination between lame and non-lame horses will need adjustment on the circle due to the observed asymmetry bias.
Risk factors for equine laminitis: A systematic review with quality appraisal of published evidence
Source: The Veterinary Journal, Available online 20 November 2011
Claire E. Wylie, Simon N. Collins, Kristien L.P. Verheyen, J. Richard Newton
Epidemiological studies into the risk factors for naturally-occurring equine laminitis are limited. There are a small number of such studies, although the results are inconsistent and remain disputed. The reasons for the conflicting results remain unclear. The aim of this review was to critically evaluate previous research in order to identify publications which provide the best evidence of risk factors for naturally-occurring equine laminitis. A systematic review of English language publications was conducted using MEDLINE (1950–2010), CAB Direct (1910–2010) and IVIS (1997–2010). Additional publications were included by searching bibliographies. Search terms included laminitis, equine, risk factors and epidemiology. Publications which compared a case population to a control population and made inferences about parameters as risk factors for naturally-occurring equine laminitis were included. Information was extracted using predefined data fields, including 18 study quality indicators.In total, 17 publications were fully appraised. Six were considered to provide the most reliable information about risk factors for naturally-occurring laminitis. Information on signalment was well researched and there was good evidence for an association with chronic laminitis and increasing age. There remain inconsistent results for many other horse-level risk factors including gender, breed and bodyweight. Previous publications estimating risk factors for equine laminitis were of reasonable quality, although they were limited in the number and scope of the risk factors studied. High-quality, evidence-based studies are needed to identify further risk factors and to establish consensus over previously identified risk factors for different equine populations.
Comparison of Analgesic Effects of Caudal Epidural 0.25% Bupivacaine with Bupivacaine Plus Morphine or Bupivacaine Plus Ketamine for Analgesia in Conscious Horses
Source: Journal of Equine Veterinary Science, Available online 20 November 2011
Rafael DeRossi, Tiago J.C. Módolo, Ronaldo C. Pagliosa, Paulo H.A. Jardim, Felipe B. Maciel, ...
The aim of this study was to compare the effects of caudal epidural bupivacaine alone (BP), bupivacaine plus morphine (BPMP), and bupivacaine plus ketamine (BPKE) for perineal analgesia in horses. Each of the six saddle horses received a caudal epidural catheter and underwent 3 treatments: BP, 0.25% (0.04 mg/kg) bupivacaine hydrochloride without epinephrine; BPMP, 0.02 mg/kg of bupivacaine combined with 0.1 mg/kg of morphine-preservative free; and BPKE, 0.02 mg/kg of bupivacaine combined with 0.5 mg/kg of ketamine. The order of treatments was randomized. The cardiovascular system, respiratory rate, quality of analgesia, sedation, and motor blockade were assessed before drug administration (baseline), at 5, 10, 15, and 30 minutes, and every 30 minutes thereafter until loss of analgesia. The median time to onset of analgesia was 5 minutes after BP treatment, faster than after BPKE or BPMP treatments, which were 10 minutes and 15 minutes, respectively (P< .05). The BPMP treatment produced analgesia (315 minutes) for a longer duration than BP treatment (210 minutes) or BPKE treatment (240 minutes), in the regions of the tail, perineum, and upper hind limb in horses. All treatments presented mild sedation or motor blockade. There were minimal effects on the cardiovascular system and respiratory rate. BPMP may be preferable to a high dose of BP or BPKE. Caudal epidural BPMP can be an appropriate choice for regional perineal analgesia in horses.
Various Circumstances Regarding Initial Allergen Exposure and Their Influence on Development of Insect Bite Hypersensitivity in Horses
Source: Journal of Equine Veterinary Science, Available online 20 November 2011
Beatrix Sommer-Locher, Verena Endriss, Ella Fromm
Insect bite hypersensitivity (IBH), an allergic reaction to the saliva of Culicoides, occurs in all horse breeds and is a severe problem. In this study, we aimed at exploring whether exterior conditions, such as duration of allergenic exposure during the first summer and age of the horses at the time of import, influence the development of IBH. Additionally, data were analyzed regarding the period IBH started after birth and after import. Datasets for 582 horses were collected. The horses were locally born Icelandic horses and horses of other breeds with IBH, as well as imported Icelandic horses, both affected and nonaffected. For locally born horses, time of birth and duration of allergen exposure during the first summer had no influence on the prevalence of IBH. The disease started mostly in their third year of life. The majority of the imported horses affected caught IBH during their first year in Central Europe. Older imported horses seemed to develop IBH quicker than younger animals. Animals imported in their first winter are exposed to the allergen when they are at least 7 months old. They experienced approximately the same low risk of developing IBH as locally bred horses. The risk of IBH increased with the horses’ age at import. From our data, we conclude that the period to develop successful immune tolerance goes beyond the perinatal phase and is longer than formerly supposed.
Consequences of Intrauterine Enrofloxacin Infusion on Mare Endometrium
Source: Journal of Equine Veterinary Science, Available online 20 November 2011
Jacobo S. Rodriguez, Sushan Han, Samuel Nielsen, Lisa K. Pearson, John M. Gay, ...
Endometritis is an important cause of infertility in mares. Enrofloxacin is a broad-spectrum antibiotic to which most equine endometritis pathogens are not resistant. The objective of this study was to determine whether enrofloxacin is safe to use as a conventional intrauterine infusion treatment. Nine healthy mares received intrauterine infusions of enrofloxacin (Baytril 100, 100 mg/mL, Bayer Health Care LLC, Animal Health Division) at 2.5 mg/kg daily for 3 days. Ultrasonographic examination and vaginal examinations were performed during the study. Endometrial biopsies were performed before treatment (S0) and 24 hours after the last treatment (S1) to evaluate acute effects. For evaluating chronic effects, biopsies were performed at 14 days (S2) and 60 days posttreatment (S3). Biopsies were graded histologically by the Kenny and Doig category scale. Difference in histological biopsy grade before and after treatment was compared between biopsies by using a repeated-measures one-way analysis of variance. and significant changes in grades were used to assess treatment effects. The vaginal and ultrasonographic examination after intrauterine infusion of enrofloxacin showed that all mares had severe purulent vaginitis and uterine fluid accumulation of ≥2 cm, with ≥1.5-cm thickening of the endometrial wall which persisted in most mares until the end of the study. Histologically, there was acute endometrial ulceration, necrosis, and hemorrhage in biopsy S1 in all mares, categorized as grade III. In biopsy S2, most mares developed fibrosis and inflammation graded as IIb (four of nine mares) or III (four of nine mares). In biopsy S3, fibrosis was extensive and had variable inflammation, graded as IIb (two of nine mares) or III (five of nine mares), with some mares healing to grade IIa (two of nine mares). There was an overall worsening of endometrial biopsy grade from I to III at S3 compared with S0 (P< .001). These results confirm that enrofloxacin is not suitable for conventional intrauterine infusion treatment in mares.
Pharmacokinetics and pharmacodynamics of intravenous medetomidine in the horse
Abstract
Objective To describe the pharmacodynamics and pharmacokinetics following an intravenous (IV) bolus dose of medetomidine in the horse.
Study design Prospective experimental trial.
Animals Eight, mature healthy horses age 11.7 ± 4.6 (mean ± SD) years, weighing 557 ± 54 kg.
Methods Medetomidine (10 μg kg−1) was administered IV. Blood was sampled at fixed time points from before drug administration to 48 hours post administration. Behavioral, physiological and biochemical data were obtained at predetermined time points from 0 minutes to 24 hours post administration. An algometer was also used to measure threshold responses to noxious stimuli. Medetomidine concentrations were determined by liquid chromatography-Mass Spectrometry and used for calculation of pharmacokinetic parameters using noncompartmental and compartmental analysis.
Results Pharmacokinetic analysis estimated that medetomidine peaked (8.86 ± 3.87 ng mL−1) at 6.4 ± 2.7 minutes following administration and was last detected at 165 ± 77 minutes post administration. Medetomidine had a clearance of 39.6 ± 14.6 mL kg−1 minute−1 and a volume of distribution of 1854 ± 565 mL kg−1. The elimination half-life was 29.1 ± 12.5 minutes. Glucose concentration reached a maximum of 176 ± 46 mg dL−1 approximately 1 hour post administration. Decreased heart rate, respiratory rate, borborygmi, packed cell volume, and total protein concentration were observed following administration. Horses lowered their heads from 107 ± 12 to 20 ± 10 cm within 10 minutes of drug administration and gradually returned to normal. Horse mobility decreased after drug administration. An increased mechanical threshold was present from 10 to 45 minutes and horses were less responsive to sound.
Conclusion and clinical relevance Behavioral and physiological effects following intravenous administration positively correlate with pharmacokinetic profiles from plasma medetomidine concentrations. Glucose concentration gradually transiently increased following medetomidine administration. The analgesic effect of the drug appeared to have a very short duration.
Development of a xylazine constant rate infusion with or without butorphanol for standing sedation of horses
Abstract
Objective To elaborate constant rate infusion (CRI) protocols for xylazine (X) and xylazine/butorphanol (XB) which will result in constant sedation and steady xylazine plasma concentrations.
Study design Blinded randomized experimental study.
Animals Ten adult research horses.
Methods Part I: After normal height of head above ground (HHAG = 100%) was determined, a loading dose of xylazine (1 mg kg−1) with butorphanol (XB: 18 μg kg−1) or saline (X: equal volume) was given slowly intravenously (IV). Immediately afterwards, a CRI of butorphanol (XB: 25 μg kg−1 hour−1) or saline (X) was administered for 2 hours. The HHAG was used as a marker of depth of sedation. Sedation was maintained for 2 hours by additional boluses of xylazine (0.3 mg kg−1) whenever HHAG >50%. The dose of xylazine (mg kg−1 hour−1) required to maintain sedation was calculated for both groups. Part II: After the initial loading dose, the calculated xylazine infusion rates were administered in parallel to butorphanol (XB) or saline (X) and sedation evaluated. Xylazine plasma concentrations were measured by HPLC-MS-MS at time points 0, 5, 30, 45, 60, 90, and 120 minutes. Data were analyzed using paired t-test, Wilcoxon signed rank test and a 2-way anova for repeated measures (p < 0.05).
Results There was no significant difference in xylazine requirements (X: 0.69, XB: 0.65 mg kg−1 hour−1) between groups. With treatment X, a CRI leading to prolonged sedation was developed. With XB, five horses (part I: two, part II: three) fell down and during part II four horses appeared insufficiently sedated. Xylazine plasma concentrations were constant after 45 minutes in both groups.
Conclusion Xylazine bolus, followed by CRI, provided constant sedation. Additional butorphanol was ineffective in reducing xylazine requirements and increased ataxia and apparent early recovery from sedation in unstimulated horses.
Clinical relevance Data were obtained on unstimulated healthy horses and extrapolation to clinical conditions requires caution.
Cryotherapy Methods to Treat Laminitis
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Metabolic Causes of Encephalopathy in Horses
Update on Infectious Diseases Affecting the Equine Nervous System
Guttural Pouch Diseases Causing Neurologic Dysfunction in the Horse
Evaluation and Management of the Recumbent Adult Horse
Toxins and Adverse Drug Reactions Affecting the Equine Nervous System
Miscellaneous Neurologic or Neuromuscular Disorders in Horses
Neuro-ophthalmology in Horses
Advanced Imaging of the Nervous System in the Horse
Lesions of the Equine Neck Resulting in Lameness or Poor Performance
Differentiation of Ataxic and Orthopedic Gait Abnormalities in the Horse
The Pros and Cons of Horse Slaughter Part 2
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Pulmonary inflammation due to exercise-induced pulmonary haemorrhage in Thoroughbred colts during race training
Source: The Veterinary Journal, Volume 190, Issue 2, November 2011, Pages e3-e6
Pedro V. Michelotto, Luis A. Muehlmann, Ana L. Zanatta, Eloyse W.R. Bieberbach, Marcelo Kryczyk, ...
This study investigated the putative roles of inflammation and platelet-activating factor (PAF) in exercise-induced pulmonary haemorrhage (EIPH). Two-year-old Thoroughbred colts (n = 37) were exercised on a racetrack for 5 months before commencement of the study. Each colt was then exercised at 15–16 m/s over 800–1000 m and broncho-alveolar lavage fluid (BALF) was collected 24 h later. The colts were subsequently divided into two groups on the basis of BALF analysis; an EIPH-positive group (presence of haemosiderophages,n = 23) and an EIPH-negative group (absence of haemosiderophages,n = 14). BALF from the EIPH-positive group had a significantly higher protein concentration (0.39 ± 0.28 vs. 0.19 ± 0.12 mg/mL,P = 0.031), higher PAF bioactivity (0.18 ± 0.12 vs. 0.043 ± 0.05 340:380 nm ratio,P = 0.042) and a higher lipid hydroperoxide concentration compared to the EIPH-negative group. There was also a lower nitrite concentration and reduced production of superoxide anion and hydrogen peroxide by alveolar macrophages in the EIPH-positive group. There was evidence of pulmonary inflammation and a decreased innate immune response of alveolar macrophages in EIPH-positive colts compared with the EIPH-negative group.
A study of sub-occlusal secondary dentine thickness in overgrown equine cheek teeth
Source: The Veterinary Journal, Available online 21 November 2011
R. Marshall, D.J. Shaw, P.M. Dixon
The presence of cheek tooth loss or defects, with subsequent overgrowth of the opposing teeth, is common in horses. Little is known about the factors that control the deposition of sub-occlusal secondary dentine (SO2D) in normal equine teeth, but these are likely to include stimulation of the occlusal surface. There appears to be no information on the possible alterations to this process when teeth develop overgrowths and, consequently, of the net effect on SO2D thickness caused by reduced stimulation of the occlusal surface and of absent/reduced normal occlusal wear (attrition). Knowledge of the likely thickness of SO2D in overgrown teeth may help reduce the risks of pulp horn exposure or thermal damage during therapeutic reduction of overgrowths.This study utilised 24 permanent cheek teeth (CT) with overgrowths (mean overgrowth height: 9.5 mm; range, 3.4−17.9 mm), and 18 control CT obtained from 15 horses of different breeds and ages. The thickness of SO2D was measured above 94 matched pulp horns in control and overgrown CT and showed a mean value of 12.14 mm (range 1.87–36.02 mm) in overgrown teeth and of 10.25 mm (range 2.64–17.26 mm) in controls. There was no significant difference between SO2D thickness in overgrown (mean 11.38 mm) and control (11.41 mm) mandibular CT, but SO2D was significantly thicker in overgrown (mean 12.57 mm) as compared to control maxillary (9.41 mm) CT. A comparison of SO2D thickness above the 94 matched pulp horns in overgrown and control teeth showed that 49% (46/94) of pulps in overgrown teeth had less SO2D overlying them than had control teeth. Of major clinical relevance was that the height of dental overgrowths was greater than SO2D thickness over one or more pulp horns in 14/24 overgrown teeth. Consequently, reduction of these overgrown teeth to the level of adjacent normal-height teeth would cause occlusal pulp exposure in 58% of teeth, in addition to possible thermal damage to additional pulp horns. It was concluded that equine CT overgrowths should be gradually reduced, by a few millimetres at a time, over a prolonged period.
Indiana equine industry accounts for over $2-billion
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Megadeth's Dave Mustaine Counts a Miniature Horse Among His ...
Loudwire
Pfizer Donates $25000 to AAEP Foundation Memorial Program
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Treeless vs. Conventional Saddles: Back Pressure Evaluated
Wednesday, November 16, 2011
Race-Day Medication Pros and Cons Debated
Researchers are testing virus-based osteoarthritis treatment in horses
Internet pet pharmacies have improved over the years, but unscrupulous sites off...
Buying pet medications online might save money but be aware of risks
www.pennlive.com
Comparing prices and pharmacies and shopping online for a pet's medications is a popular option, but being an informed shopper is the key to saving the family pet a world of trouble.
Conventional vs. Natural Training: Which is Less Stressful?
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Treating Respiratory Diseases Horse Course Archived
Equine Degenerative Myeloencephalopathy in Lusitano Horses
Background
Equine degenerative myeloencephalopathy (EDM) is a neurodegenerative disorder that has been previously associated with low vitamin E concentrations.
Objective
To describe the clinical, electrophysiologic, and pathologic features of EDM in a group of related Lusitano horses.
Animals
Fifteen Lusitano horses.
Procedures
Neurologic examinations were conducted, and serum vitamin E concentrations were measured. Three neurologically abnormal horses were further evaluated by ophthalmologic examination, electroretinography, electroencephalography, muscle and nerve biopsies, and post-mortem examination.
Results
Six horses appeared neurologically normal, 6 were neurologically abnormal, and 3 had equivocal gait abnormalities. Abnormal horses demonstrated ataxia and paresis. An inconsistent menace response was noted in 4 neurologically abnormal horses and in 1 horse with equivocal findings. All horses had low serum vitamin E concentrations (<1.5 ppm). Ophthalmologic examinations, electroretinograms, electroencephalograms, and muscle and peripheral nerve biopsies were unremarkable in 3 neurologically abnormal horses. At necropsy, major neuropathological findings in these horses were bilaterally symmetric, severe, neuro axonal degeneration in the gracilis, cuneatus medialis, cuneatus lateralis, and thoracicus nuclei and bilaterally symmetric axonal loss and demyelination mainly in the dorsolateral and ventromedial tracts of the spinal cord. A diagnosis of EDM was made based on these findings. Pedigree analysis identified 2 sires among the affected horses.
Conclusions and Clinical Relevance
Equine degenerative myeloencephalopathy is a neurodegenerative disorder that causes ataxia and, in severe cases, paresis, in young Lusitano horses. The disease appears to have a genetic basis, and although vitamin E deficiency is a common finding, low serum vitamin E concentrations also may occur in apparently unaffected related individuals.
Horses most likely to be injured in pasture - research
Towards a new treatment for equine acute laminitis: The importance of signalling pathways
Source: The Veterinary Journal, Available online 16 November 2011
John D. Mitchell, Jonathan Elliott
DOJ challenges ruling in veterinary compounding case
Tuesday, November 15, 2011
Lecture on Causes of Collapse in the Horse Scheduled
Nutritional Support for Horse Hooves
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U.S. Equestrian Federation modifies veterinary rules on NSAID use in competition horses
restrict use to a single non-steroidal anti-inflammatory drug (NSAID).
KY Meeting Shows Deep Divide Over Salix Use
Sunday, November 13, 2011
Gait analysis using 3D accelerometry in horses sedated with xylazine
Source: The Veterinary Journal, Available online 13 November 2011
F.J. López-Sanromán, R. Holmbak-Petersen, I. Santiago, I.A. Gómez de Segura, E. Barrey
The aim of the present study was to verify the efficacy and sensitivity of an accelerometric device in detecting and quantifying the degree of movement alteration produced in horses sedated with xylazine. Horses (n = 6) were randomly administered either xylazine or a control by intravenous injection, with at least 1 week between each treatment. A triaxial accelerometric device was used for the accelerometric gait assessment 15 min before (baseline) and 5, 15, 30, 45, 60, 75, 90, 105 and 120 min after each treatment. Eight different accelerometric parameters were calculated, including speed, stride frequency, stride length, regularity, dorsoventral power, propulsion power, mediolateral power and total power, with the force of acceleration and the dorsoventral, mediolateral and craniocaudal (propulsive) parts of the power then calculated.Administration of xylazine decreased many of the parameters investigated, with significant differences for speed, stride frequency, dorsoventral power, propulsion power and total power at 5, 15, 30 and 45 min after injection. There were no significant differences in stride length values at any time point. Decreases in regularity values were evident with significant differences at every time point from 5 to 120 min following xylazine injection. Force values were also significantly reduced from 5 to 30 min after treatment and a redistribution of the total power was observed 5 min after injection as the mediolateral power increased significantly, while the dorsoventral power decreased. Accelerometry offers a practical, accurate, easy to use, portable and low cost method of objectively monitoring gait abnormalities at the walk in horses after sedation with xylazine.
Iowa approves at-home horse bets
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Joint Infection Risk and Other 2011 Sports Medicine Studies
Lots of Questions, Few Answers for Show Jumpers
USEF President David O'Connor called for a 25-year-look at show jumping and what it should be going forward. While the continuing process also will be followed by the organization's other disciplines, show jumping appears to be the one that is in real ... See all stories on this topic » | The Star-Ledger - NJ.com |
Five and 60-Second Flexion Tests Yield Similar Results
UHC Operation Gelding Continues with More Castration Clinics
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Friday, November 11, 2011
Pfizer Animal Health Supports ... - Equine Resources International, LLJ
www.equineresources.com/.../322-pfizer-animal-health-suppor...
"Blood rule" to be discussed at FEI General Assembly
Inside a Lameness Exam
Pay Homage to War Horses This Veteran's Day
2011 Equine Affaire & Pfizer Fantasia
Second FL Group Applies for Barrel Racing
ASPCA veterinarian suspended without pay after clarifying comments on NYC carriage horse death
suspended by ASPCA after revising her statement about the death of a carriage horse.
Race-Day Drugs Focus of Kentucky Meeting
Thursday, November 10, 2011
A prospective longitudinal study of naturally infected horses to evaluate the performance characteristics of rapid diagnostic tests for equine influenza virus
Source: Veterinary Microbiology, Available online 6 November 2011
A.J. READ, K.E. ARZEY, D.S. FINLAISON, X. GU, R.J. DAVIS, ...
An outbreak of equine influenza (EI) occurred in Australia in 2007. During the laboratory support for this outbreak, real-time reverse transcriptase polymerase chain reaction (qRT-PCR) assays and a blocking enzyme linked immunosorbent assay (bELISA) were used as testing methods to detect infection with the virus. The qRT-PCR and bELISA tests had not been used for EI diagnosis before, so it was not known how soon after infection these tests would yield positive results, nor for how long these results would remain positive. To answer these questions, nasal swabs and blood samples were collected daily from a group of 36 naturally infected horses. EI viral RNA was detected in all horses by qRT-PCR from the first to tenth day after clinical signs were evident, and was detected in some horses for up to 34 days. Antibody was detected in the bELISA in some horses by day 3, with a median time to seroconversion of 5 days. The results from this study indicate that viral RNA can be detected from nasal swabs for much longer than infectious virus is thought to be shed from horses. The bELISA detected antibodies against EI virus in all horses for 139 days following infection, but only detected approximately 50% of horses 12 months following infection. Haemagglutination inhibition testing detected antibodies against H3 antigens in all horses for 28 days following infection, but 2 were negative by 35 days following infection.
Ancient DNA provides new insights into cave paintings of horses
Ultrasonographic appearance of bony abnormalities at the dorsal aspect of the fetlock joint in geriatric cadaver horses
Source: The Veterinary Journal, Available online 9 November 2011
K. Vanderperren, I. Gielen, A. Van Caelenberg, E. Van der Vekens, E.V. Raes, ...
This article describes the ultrasonographic (US) appearance of bony abnormalities on the dorsal aspect of the third metacarpal/metatarsal bone of the equine fetlock in cadavers with radiographic signs of osteoarthrosis. After US, computed tomography was undertaken to better characterise the lesions. Twelve fetlock joints were collected and all had more than one bone abnormality on US. Normal subchondral bone appeared on US as a well-defined and regular hyperechoic line with distal acoustic shadowing.Bone abnormalities detected on US included (1) gaps in the proximal subchondral bone filled with material of heterogeneous echogenicity, (2) bone fragments represented as small straight smoothly delineated hyperechoic lines with distal shadowing located superficial to the surface of the adjacent bone, (3) proximal new bone formation visible as mild to severe cortical protrusions, (4) marginal osteophytoses seen as an elevation of the hyperechoic surface of the subchondral bone at the edges of the joint surfaces, (5) indentations in subchondral bone seen as a concave deviation of the hyperechoic line without interruption, (6) focal or diffuse irregularities of the subchondral bone seen as disruptions of the normal smooth bony contours, and (7) focal hyperechoic spikes originating from the subchondral plate and invading the articular cartilage. These findings are discussed.
Behavior of Horses With, Without Gastric Ulcers Compared
Dental Health and the Performance Horse
Pfizer Opens New Equine Research Center in Michigan
AVMA supports new NSAID rule for competition horses
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Winter Health Care
Help your horse stay healthy in colder temperatures.
Horse owners and managers need to pay close attention to their horses’ body condition, particularly as temperatures drop. Journal photo.
From AQHA Corporate Partner Pfizer
Maintaining a healthy horse through rigorous show schedules and mosquito season can be difficult.
However, adding in winter elements such as cooler temperatures, snow and ice can present a whole new set of challenges.
Whether your American Quarter Horse is at a breeding facility, a show barn or pastured, there are steps horse owners and managers can take to manage their horses for optimal health this winter.
Wind and cooler temperatures often mean closed-up facilities. Making sure horses have enough ventilation is important to helping prevent disease. Practicing good barn hygiene, both at home and on the road, can also help protect horses. Whenever possible, avoid sharing water buckets, lip chains, halters or other items that might touch the horse’s mouth, nose and ears. If items have to be shared, be sure to follow proper sanitation and disinfection techniques first. There are a number of commercially available disinfectants, such as ROCCAL® D PLUS and NOLVASAN® SOLUTION that are effective for killing bacteria. Veterinarians also recommend that every barn offer a shallow basin full of properly prepared disinfectant for people to wash their boots before entering or leaving a facility.
Ensuring that a horse has enough water is also important. Horses sometimes tend to drink less when the weather is colder. If a water bucket or trough is frozen, be sure to break and dump out the ice. Keeping the water temperature above 45 degrees F will encourage horses to drink during cold weather.
AQHA’s FREE HYPP Survival Guide will teach you how to be prepared for and deal with a horse affected by HYPP.
Horse owners and managers need to pay close attention to their horses’ body condition all year, but particularly as temperatures drop. In the winter months, horses no longer have the nutrients in lush grass to supplement their diet. Therefore, making sure they have adequate, good-quality hay can help maintain an optimum body score. Depending on the horses’ work schedule, their grain intake may need to be gradually increased or decreased. Any changes in diet should be done gradually and in consultation with a veterinarian first, as sudden changes in diet may increase the risk of colic.
Keeping horses comfortable and body temperature regulated is critical in winter health care management. If a horse gets cold and/or wet, he may have to exert excess digestive energy to keep warm. Blanketing may offer a solution but may not be necessary in some circumstances. If the horse has established a natural winter coat, it acts as its own insulation. However, if it is a show horse who has been clipped or the hair kept shorter to reduce sweating, then blanketing is probably necessary. If a horse is outside and gets wet from snow or rain, it is imperative to put on a dry blanket and to make sure his coat is dry before putting on the blanket. Also, be sure the horse has been properly cooled and his coat is dry after a rigorous workout.
Learn all about this dominant genetic disease in AQHA’s FREE HYPP Survival Guide report.
Having every horse on a routine schedule makes it easier to maintain all year. Barn managers and owners should also work with their veterinarian to implement a strategic deworming program and make sure their horses are current on vaccinations.
Unfortunately, this can be the time of year when upper respiratory disease such as equine influenza virus can become a problem in facilities. The best method for helping protect horses against equine influenza is to have them vaccinated by a veterinarian. Pfizer Animal Health’s FLUVAC INNOVATOR® helps provide protection against equine influenza virus. In addition, FLUVAC INNOVATOR vaccines also contain equine herpesvirus, types 1 and 4, to help protect against rhinopneumonitis.
Maintaining healthy horses in the winter months can present challenges for equine caregivers. As basic as most precautionary measures may seem, they are critical to protecting the overall wellness of each horse and the barn as a whole. Preventative care and basic hygiene also protect a horse’s health when traveling to winter venues where he is exposed to other horses and potential disease. By working with a veterinarian to create a wellness program that incorporates parasite control, vaccinations, routine veterinary care, dental exams, nutritional counseling and barn hygiene, equine caregivers can provide their horses with the best opportunity to achieve optimal health even in the coldest temperatures.
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